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TRPM7 Channel-Mediated Mitochondrial Oxidative Stress Induces Dysfunction of Müller Cells Under High Glucose and Low Mg2+ Stress

Background:Clinical epidemiological data have shown that hypomagnesemia, defined as a serum Mg2+ concentration of <0.7 mmol/L, independently increases the risk of diabetic retinopathy (DR) in patients with type 2 diabetes mellitus (T2DM). The molecular and cellular mechanisms through which hypomagne...

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Principais autores: Ping Liu, Zhen Guo, Jun Zhou, Lin Mou, Dongchuan Zuo, Junguo Duan
פורמט: Artigo
שפה:Inglês
יצא לאור: IMR Press 2026-06-01
סדרה:Frontiers in Bioscience-Landmark
נושאים:
diabetic retinopathy
magnesium
trpm cation channel
oxidative stress
גישה מקוונת:https://www.imrpress.com/journal/FBL/31/6/10.31083/FBL50306
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