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Polymorphism of FTO rs1421085 as risk of metabolic syndrome; case-control study in two ethnics, Javanese and Malay population, Indonesia

Abstract Background Metabolic syndrome (MetS) represents a complex interplay between genetic predisposition, adiposity, and lifestyle determinants. The fat mass and obesity-associated (FTO) gene variant rs1421085 has been linked to obesity and metabolic disturbances; however, evidence from Indonesia...

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Principais autores: Anggelia Puspasari, Citra Maharani, Pramudji Hastuti, Ahmad Hamim Sadewa, Rosdiana Mus, Rina Nofri Enis, Rita Halim, Tengku Arief Buana Perkasa, Nyimas Natasha Ayu Shafira
Formato: Artigo
Idioma:Inglês
Publicado em: SpringerOpen 2025-11-01
coleção:Egyptian Journal of Medical Human Genetics
Assuntos:
FTO rs1421085
Metabolic syndrome
Polymorphism
Nutrigenetic
Adiposity
Javanese
Acesso em linha:https://doi.org/10.1186/s43042-025-00810-8
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