Liver as a new target organ in Alzheimer’s disease: insight from cholesterol metabolism and its role in amyloid-beta clearance

Alzheimer’s disease, the primary cause of dementia, is characterized by neuropathologies, such as amyloid plaques, synaptic and neuronal degeneration, and neurofibrillary tangles. Although amyloid plaques are the primary characteristic of Alzheimer’s disease in the central nervous system and periphe...

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Detalhes bibliográficos

Principais autores:	Beibei Wu, Yuqing Liu, Hongli Li, Lemei Zhu, Lingfeng Zeng, Zhen Zhang, Weijun Peng
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wolters Kluwer Medknow Publications 2023-12-01
coleção:	Neural Regeneration Research
Assuntos:	abca1 alzheimer’s disease amyloid-beta apolipoprotein e cholesterol metabolism liver liver x receptor low-density lipoprotein receptor-related protein 1 peripheral clearance tauroursodeoxycholic acid
Acesso em linha:	https://journals.lww.com/10.4103/1673-5374.391305
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