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In vivo safety and biodistribution profile of Klotho-enhanced human urine-derived stem cells for clinical application

Abstract Background Urine-derived stem cells (UDSCs) can be easily isolated from urine and possess excellent stem cell characteristics, making them a promising source for cell therapeutics. Due to their kidney origin specificity, UDSCs are considered a superior therapeutic alternative for kidney dis...

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Principais autores: Sang-Heon Kim, Sung-Hoon Lee, Jeong-Ah Jin, Hyung-Joon So, Jae-Ung Lee, Min-Jae Ji, Eun-Joong Kwon, Pyo-Sung Han, Hong-Ki Lee, Tae-Wook Kang
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2023-12-01
coleção:Stem Cell Research & Therapy
Assuntos:
Urine-derived stem cells (UDSCs)
Safety
Toxicity
Distribution
Tumorigenicity
Klotho
Acesso em linha:https://doi.org/10.1186/s13287-023-03595-y
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