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The application and prospect of granzyme B-targeted PET imaging in cancer immunotherapy

Abstract In the context of cancer immunotherapy, assessing treatment response and predicting survival outcomes remain major challenges. Granzyme B (GZMB), released by cytotoxic T cells, represents the terminal effector event of activated antitumor immunity, thereby providing a robust rationale for G...

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Autori principali: Xu Tong, Ying Jiang, Nan Bi
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2025-12-01
Serie:Journal of Translational Medicine
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Accesso online:https://doi.org/10.1186/s12967-025-07419-w
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