Infectious complications distribution following CLL1 CAR-T cell therapy for acute myeloid leukemiass

Abstract The CLL1-targeted chimeric antigen receptor T (CAR-T) cell therapy offers a novel therapeutic approach for refractory or relapsed acute myeloid leukemia (AML).The targeted elimination of tumor cells by CLL1 CAR-T therapy also induces cytotoxic effects on neutrophils, leading to a severe gra...

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Huvudupphov:	Jianmei Xu, Huan Zhang, Yifan Zhao, Xiaomei Zhang, Shujing Guo, Xiaoxue Shi, Xia Xiao, Hairong Lyu, Yu Zhang, Xiaoyuan He, Mingfeng Zhao
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	Springer 2025-03-01
Serie:	Cancer Immunology, Immunotherapy
Ämnen:	Infection Prevention CLL1 CAR-T Cytokine release syndrome Acute myeloid leukemia
Länkar:	https://doi.org/10.1007/s00262-025-03998-1
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