Sharpin suppresses β1-integrin activation by complexing with the β1 tail and kindlin-1
Abstract Background Previously sharpin has been identified as an endogenous inhibitor of β1-integrin activation by directly binding to a conserved region in the cytoplasmic tails (CTs) of the integrin β1-associated α subunits. Methods Here we employed biochemical approaches and cellular analyses to...
Kaydedildi:
| Asıl Yazarlar: | , , , , , , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
BMC
2019-08-01
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| Seri Bilgileri: | Cell Communication and Signaling |
| Konular: | |
| Online Erişim: | http://link.springer.com/article/10.1186/s12964-019-0407-6 |
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