Secretion of transthyretin: molecular mechanisms dependent on the endoplasmic reticulum
Hereditary transthyretin amyloidosis (ATTRv) results from genetic mutations that destabilize transthyretin (TTR), leading to the formation of extracellular aggregates and amyloid fibrils. A common pathological feature of ATTRv is the capacity of TTR variants to evade endoplasmic reticulum quality co...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
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Frontiers Media S.A.
2025-07-01
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| Serie: | Frontiers in Physiology |
| Soggetti: | |
| Accesso online: | https://www.frontiersin.org/articles/10.3389/fphys.2025.1623185/full |
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