Chemotherapy triggers cachexia by deregulating synergetic function of histone‐modifying enzymes

Abstract Background Chemotherapy is the first line of treatment for cancer patients. However, the side effects cause severe muscle atrophy or chemotherapy‐induced cachexia. Previously, the NF‐κB/MuRF1‐dependent pathway was shown to induce chemotherapy‐induced cachexia. We hypothesized that acute col...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Mamta Amrute‐Nayak, Gloria Pegoli, Tim Holler, Alfredo Jesus Lopez‐Davila, Chiara Lanzuolo, Arnab Nayak
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Wiley 2021-02-01
Sarja:	Journal of Cachexia, Sarcopenia and Muscle
Aiheet:	Chemotherapy‐induced cachexia Epigenetics Muscle atrophy p300 Sarcomere organization SENP3
Linkit:	https://doi.org/10.1002/jcsm.12645
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