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Kaempferol Ameliorates Oxygen-Glucose Deprivation/Reoxygenation-Induced Neuronal Ferroptosis by Activating Nrf2/SLC7A11/GPX4 Axis

Kaempferol has been shown to protect cells against cerebral ischemia/reperfusion injury through inhibition of apoptosis. In the present study, we sought to investigate whether ferroptosis is involved in the oxygen-glucose deprivation/reperfusion (OGD/R)-induced neuronal injury and the effects of kae...

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Principais autores: Yuan Yuan, Yanyu Zhai, Jingjiong Chen, Xiaofeng Xu, Hongmei Wang
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2021-06-01
coleção:Biomolecules
Assuntos:
ischemic stroke
kaempferol
Nrf2
GPX4
lipid peroxidation
ferroptosis
Acesso em linha:https://www.mdpi.com/2218-273X/11/7/923
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