A LY6E-PHB1-TRIM21 assembly degrades CD14 protein to mitigate LPS-induced inflammatory response

Summary: A major theme of host against invading pathogens lies in multiple regulatory nodes that ensure sufficient signals for protection while avoiding excessive signals toward over-inflammation. The TLR4/MD-2/CD14 complex receptor-mediated response to bacterial lipopolysaccharide (LPS) represents...

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Bibliografische Detailangaben

Hauptverfasser:	Xinyu Zhu, Linxia Zhang, Daobin Feng, Lang Jiang, Peng Sun, Chen Zhao, Xiaoyan Zhang, Jianqing Xu
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Elsevier 2023-06-01
Schriftenreihe:	iScience
Schlagworte:	Immunology Molecular biology
Online-Zugang:	http://www.sciencedirect.com/science/article/pii/S2589004223008854
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