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New Hydroxycinnamic Acid Esters as Novel 5-Lipoxygenase Inhibitors That Affect Leukotriene Biosynthesis

Leukotrienes are inflammatory mediators that actively participate in the inflammatory response and host defense against pathogens. However, leukotrienes also participate in chronic inflammatory diseases. 5-lipoxygenase is a key enzyme in the biosynthesis of leukotrienes and is thus a validated thera...

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Главные авторы: Luc H. Boudreau, Grégoire Lassalle-Claux, Marc Cormier, Sébastien Blanchard, Marco S. Doucet, Marc E. Surette, Mohamed Touaibia
Формат: Artigo
Язык:Inglês
Опубликовано: Wiley 2017-01-01
Серии:Mediators of Inflammation
Online-ссылка:http://dx.doi.org/10.1155/2017/6904634
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