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In-situ proliferation contributes to the accumulation of myeloid cells in the spleen during progressive experimental visceral leishmaniasis.

Visceral leishmaniasis (VL) is characterized by expansion of myeloid cells in the liver and spleen, which leads to a severe splenomegaly associated with higher risk of mortality. This increased cellularity is thought to be a consequence of recruitment of cells to the viscera. We studied whether the...

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Autori principali: E Yaneth Osorio, Audrie A Medina-Colorado, Bruno L Travi, Peter C Melby
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2020-01-01
Serie:PLoS ONE
Accesso online:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0242337&type=printable
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