Single-Cell RNA Profiling Reveals Adipocyte to Macrophage Signaling Sufficient to Enhance Thermogenesis

Summary: Adipocytes deficient in fatty acid synthase (iAdFASNKO) emit signals that mimic cold exposure to enhance the appearance of thermogenic beige adipocytes in mouse inguinal white adipose tissues (iWATs). Both cold exposure and iAdFASNKO upregulate the sympathetic nerve fiber (SNF) modulator Ne...

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Autors principals:	Felipe Henriques, Alexander H. Bedard, Adilson Guilherme, Mark Kelly, Jingyi Chi, Peng Zhang, Lawrence M. Lifshitz, Karl Bellvé, Leslie A. Rowland, Batuhan Yenilmez, Shreya Kumar, Yetao Wang, Jeremy Luban, Lee S. Weinstein, Jiandie D. Lin, Paul Cohen, Michael P. Czech
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2020-08-01
Col·lecció:	Cell Reports
Matèries:	beige adipocytes de novo lipogenesis sympathetic nerve fibers stromal vascular fraction macrophage polarization
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S2211124720309839
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