Challenges of applying multicellular tumor spheroids in preclinical phase

Abstract The three-dimensional (3D) multicellular tumor spheroids (MCTs) model is becoming an essential tool in cancer research as it expresses an intermediate complexity between 2D monolayer models and in vivo solid tumors. MCTs closely resemble in vivo solid tumors in many aspects, such as the het...

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Autors principals:	Se Jik Han, Sangwoo Kwon, Kyung Sook Kim
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2021-03-01
Col·lecció:	Cancer Cell International
Matèries:	Multicellular tumor spheroids Drug screening Therapeutic efficacy High-throughput Microfluidics
Accés en línia:	https://doi.org/10.1186/s12935-021-01853-8
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