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Biochanin A prevents neurodegeneration and oxidative stress in a kainic acid model of epilepsy by activating the PI3K/Akt/Nrf2 signaling pathway

Abstract Epilepsy is a serious neurodegenerative disorder, which affects approximately 50 million people worldwide. Growing evidence indicates that oxidative stress caused by an excessive production of free radicals is considered one of the etiologies of epilepsy. Several studies have demonstrated t...

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Principais autores: Ratchaniporn Kongsui, Tichanon Promsrisuk, Teera Chanmanee, Lars Klimaschewski, Sataporn Jamsuwan, Napatr Sriraksa, Jinatta Jittiwat, Sitthisak Thongrong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Portfolio 2025-11-01
coleção:Scientific Reports
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Acesso em linha:https://doi.org/10.1038/s41598-025-23414-z
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