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Lipidome of high-density lipoprotein is strongly perturbed in hyperalphalipoproteinemia resulting from a rare mutation in endothelial lipase

Both low and extremely high concentrations of high-density lipoprotein (HDL)-cholesterol are associated with elevated cardiovascular risk. As extremely high HDL-cholesterol states of hyperalphalipoproteinemia (HALP) are rare, HDL particles in this condition remain poorly characterised. HALP may resu...

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Autori principali: Livia Pisciotta, Marie Lhomme, Chiara Pavanello, Maharajah Ponnaiah, Arianna Strazzella, Alice Ossoli, Wilfried Le Goff, Laura Calabresi, Anatol Kontush
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2025-09-01
Serie:Atherosclerosis Plus
Soggetti:
HDL
Extremely high HDL-Cholesterol
Hyperalphalipoproteinemia
Endothelial lipase
Mutations
Lipidomics
Accesso online:http://www.sciencedirect.com/science/article/pii/S2667089525000173
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