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EFFECT OF pH AND ORGANIC HYDROXYLATED ADDITIVES ON N-DESMETHYLDIAZEPAM SOLUBILIZATION BY NON-IONIC SURFACTANTS

N-desmethyldiazepam, was solubilized in different non-ionic surfactant solutions including members of polysorbates, Myrjs, Eumulgins and Brijs at 25 and 35 C. Polysorbate 80 was more efficient in solubilizing the drug than polysorbate 20 and Brij 35 was more efficient than Brij 58. On the other han...

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Detalhes bibliográficos
Principais autores: E. Samy, Aly Abdel Rahman, A. Aboutaleb
Formato: Artigo
Idioma:Inglês
Publicado em: Assiut University, Faculty of Pharmacy 1986-12-01
coleção:Bulletin of Pharmaceutical Sciences. Assiut University
Acesso em linha:https://bpsa.journals.ekb.eg/article_74583_103433ad1e827257d3a0b942d23388ae.pdf
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