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Rapid cloning-free mutagenesis of new SARS-CoV-2 variants using a novel reverse genetics platform

Reverse genetic systems enable the engineering of RNA virus genomes and are instrumental in studying RNA virus biology. With the recent outbreak of the coronavirus disease 2019 pandemic, already established methods were challenged by the large genome of severe acute respiratory syndrome coronavirus...

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Principais autores: Enja Tatjana Kipfer, David Hauser, Martin J Lett, Fabian Otte, Lorena Urda, Yuepeng Zhang, Christopher MR Lang, Mohamed Chami, Christian Mittelholzer, Thomas Klimkait
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications Ltd 2023-11-01
Serier:eLife
Fag:
SARS-CoV-2
reverse genetics
RNA virus
Chikungunya
Dengue
One Health
Online adgang:https://elifesciences.org/articles/89035
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