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The effect of interference on the CD8+ T cell escape rates in HIV

In early HIV infection, the virus population escapes from multiple CD8+ cell responses. The later an escape mutation emerges, the slower it outgrows its competition, i. e. the escape rate is lower. This pattern could indicate that the strength of the CD8+ cell responses is waning, or that later vira...

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Detalles Bibliográficos
Autores principales: Victor eGarcia, Roland Robert Regoes
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2015-01-01
Colección:Frontiers in Immunology
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Acceso en línea:http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00661/full
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