Evaluation of Micro Satellite Instability and Mismatch Repair Status in Different Solid Tumors: A Multicenter Analysis in a Real World Setting

Immune-checkpoint inhibitors (ICIs) play a key role in the treatment of advanced stage colorectal cancer (CRC) patients featuring a deficient DNA mismatch repair (dMMR) system or a high microsatellite instability (MSI-H) profile. However, beyond the established role in CRC patients, ICIs have highly...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Umberto Malapelle, Paola Parente, Francesco Pepe, Caterina De Luca, Pasquale Pisapia, Roberta Sgariglia, Mariantonia Nacchio, Gianluca Gragnano, Gianluca Russo, Floriana Conticelli, Claudio Bellevicine, Elena Vigliar, Antonino Iaccarino, Claudia Covelli, Mariangela Balistreri, Celeste Clemente, Giovanni Perrone, Angela Danza, Fabio Scaramuzzi, Matteo Fassan, Giancarlo Troncone, Paolo Graziano
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2021-07-01
Colecção:	Cells
Assuntos:	predictive molecular pathology IHC fully automated RT-PCR microfluidic MMR MSI
Acesso em linha:	https://www.mdpi.com/2073-4409/10/8/1878
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!