Factors affecting low fetal fraction in fetal screening with cell-free DNA in pregnant women: a systematic review and meta-analysis

Abstract Background Cell-Free DNA (cfDNA) is a non-invasive perinatal test (NIPT) used to assess fetal anomalies. The ability to detect fetal chromosomal aneuploidies is directly related to a sample’s fetal to total DNA fraction, known as the fetal fraction (FF). The minimum FF is considered 4%, and...

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Detalhes bibliográficos

Principais autores:	Sanaz Mousavi, Ziba Shokri, Parvin Bastani, Morteza Ghojazadeh, Sevda Riahifar, Hooman Nateghian
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2022-12-01
coleção:	BMC Pregnancy and Childbirth
Assuntos:	Low fetal fraction Cell-free DNA Fetal soft marker Fetal screening
Acesso em linha:	https://doi.org/10.1186/s12884-022-05224-7
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