Molecular mechanism underlying non-discriminatory recognition of relaxin-3 by RXFP3 and RXFP4
Abstract The human relaxin family peptide receptors RXFP3 and RXFP4 play important physiological roles through interactions with endogenous hormones, relaxin-3 and insulin-like peptide 5 (INSL5). They are implicated in certain neurological and metabolic disorders. While INSL5 only activates RXFP4, r...
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| Principais autores: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Portfolio
2025-05-01
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| Serier: | Communications Biology |
| Online adgang: | https://doi.org/10.1038/s42003-025-08220-7 |
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