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Trivalent mRNA vaccine-candidate against seasonal flu with cross-specific humoral immune response

Seasonal influenza remains a serious global health problem, leading to high mortality rates among the elderly and individuals with comorbidities. Vaccination is generally accepted as the most effective strategy for influenza prevention. While current influenza vaccines are effective, they still have...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Elena P. Mazunina, Vladimir A. Gushchin, Denis A. Kleymenov, Andrei E. Siniavin, Elena I. Burtseva, Maksim M. Shmarov, Evgenya A. Mukasheva, Evgeniia N. Bykonia, Sofia R. Kozlova, Elina A. Evgrafova, Anastasia N. Zolotar, Elena V. Shidlovskaya, Elena S. Kirillova, Anastasiya S. Krepkaia, Evgeny V. Usachev, Nadezhda A. Kuznetsova, Igor A. Ivanov, Sergey E. Dmitriev, Roman A. Ivanov, Denis Y. Logunov, Alexander L. Gintsburg
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2024-04-01
Schriftenreihe:Frontiers in Immunology
Schlagworte:
seasonal influenza
vaccine
mRNA
immunogenicity
efficacy
immune response
Online-Zugang:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1381508/full
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