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Transcription-Replication Collisions and Chromosome Fragility

Accurate replication of the entire genome is critical for cell division and propagation. Certain regions in the genome, such as fragile sites (common fragile sites, rare fragile sites, early replicating fragile sites), rDNA and telomeres, are intrinsically difficult to replicate, especially in the p...

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Bibliografiske detaljer
Principais autores: Wei Wu, Jing Na He, Mengjiao Lan, Pumin Zhang, Wai Kit Chu
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021-12-01
Serier:Frontiers in Genetics
Fag:
Online adgang:https://www.frontiersin.org/articles/10.3389/fgene.2021.804547/full
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