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Kaempferol alleviates T-cell immunosenescence and inflammaging in aged mice via the SIRT3-LKB1-AMPK-mitophagy pathway

Abstract Background Immunosenescence, characterized by progressive immune dysfunction accompanied by chronic low-grade inflammation (inflammaging), is a key driver of systemic ageing. Senescent T cells are central to this process, yet effective interventions remain limited. Kaempferol is a natural f...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Wendi Chen, Shuang Liu, Guoqiang Xu, Xin Liu, Yuxuan Shi, Guolong Wang, Yunna Ning, Chenfeng Yuan, Zhiming Lu, Yongzhi Cao, Yueran Zhao
Hōputu: Artigo
Reo:Inglês
I whakaputaina: BMC 2026-02-01
Rangatū:Immunity & Ageing
Ngā marau:
Urunga tuihono:https://doi.org/10.1186/s12979-026-00560-0
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