Transient Expression of a Recombinant Monoclonal Antibody in HEK293T Cells

Background: Monoclonal antibodies (mAbs) are considered the most important and financially successful category of the biopharmaceuticals. Extensive optimization of the expression vector, host system and culture parameters are required for the successful production of active monoclonal antibodies in...

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Hlavní autoři:	Omid Mohammadian, Masoumeh Rajabibazl, Hadi Bayat, Azam Rahimpour
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Tabriz University of Medical Sciences 2018-09-01
Edice:	Pharmaceutical Sciences
Témata:	Monoclonal antibody Internal ribosome entry site Transient expression HEK293T cells
On-line přístup:	http://journals.tbzmed.ac.ir/PHARM/Manuscript/PHARM-24-207.pdf
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