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Efbalropendekin Alfa enhances human natural killer cell cytotoxicity against tumor cell lines in vitro

IL-15 has shown preclinical activity by enhancing the functional maturation of natural killer (NK) cells. Clinical evaluation of the potential anticancer activity of most cytokines, including IL-15, has been limited by low tolerability and rapid in vivo clearance. Efbalropendekin Alfa (XmAb24306) is...

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I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Hesham M. Shehata, Pranay Dogra, Sarah Gierke, Patrick Holder, Shomyseh Sanjabi
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Frontiers Media S.A. 2024-03-01
Rangatū:Frontiers in Immunology
Ngā marau:
Urunga tuihono:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1341804/full
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