Efficacy of emergency maternal MVA-ZIKV vaccination in a rapid challenge model of lethal Zika infection

Abstract Zika virus (ZIKV) outbreak of 2015 was associated with microcephaly and congenital birth defects in children born to pregnant women infected with ZIKV. Using the highly susceptible Type I Interferon Receptor-deficient mouse-model, we demonstrate that a single emergency vaccination with a no...

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Autors principals:	Asisa Volz, Sabrina Clever, Alina Tscherne, Astrid Freudenstein, Sylvia Jany, Jan H. Schwarz, Leonard Limpinsel, William G. Valiant, Georgia Kalodimou, Gerd Sutter, Joseph J. Mattapallil
Format:	Artigo
Idioma:	Inglês
Publicat:	Nature Portfolio 2025-03-01
Col·lecció:	npj Vaccines
Accés en línia:	https://doi.org/10.1038/s41541-025-01094-0
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