GC-MS metabolite profiling and multi-target Docking analysis of Calotropis procera and Euphorbia tirucalli stem extracts for cytotoxicity and antioxidant activity

Abstract C. procera and E. tirucalli are traditionally used to treat infections, inflammation, skin disorders, and tumors. This study evaluated their cytotoxic and antioxidant activities, analyzed chemical profiles via GC-MS, and performed molecular docking against breast cancer target proteins. The...

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Principais autores:	Gashaw Nigussie, Sumera Zaib, Menberework Chanyalew, Aman Dekebo, Asfaw Meressa, Markos Abebe, Temesgen Negassa, Mo Hunsen, Milkyas Endale
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2026-01-01
coleção:	Scientific Reports
Assuntos:	Cytotoxic Antioxidant GC-MS Α-amyrin Β-amyrin Lanosterol
Acesso em linha:	https://doi.org/10.1038/s41598-025-32835-9
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