Prmt6 Deficiency or Inhibition Restores Microglial Homeostasis and Promotes Scar‐Limited Repair in Adult Spinal Cord Injury

ABSTRACT Neonatal mice achieve scar‐free healing after spinal cord injury (SCI) by restoring microglial homeostasis, unlike adults, where persistent microglial dyshomeostasis drives scar expansion through mechanisms that remain elusive. Using RNA sequencing, we identified protein arginine methyltran...

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Detalles Bibliográficos

Principais autores:	Weilin Peng, Zhengqiang Wu, Yu Xiong, Zhongya Gao, Yishan Liu, Ziyi Wang, Haibin Wang, Chaofeng Han, Wenxiang Chu, Xuhua Lu
Formato:	Artigo
Idioma:	Inglês
Publicado:	Wiley 2026-07-01
Series:	Advanced Science
Assuntos:	fatty acid oxidation homeostasis microglia PGC‐1α spinal cord injury
Acceso en liña:	https://doi.org/10.1002/advs.75325
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