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Reciprocal regulation between RACGAP1 and AR contributes to endocrine therapy resistance in prostate cancer

Abstract Background Endocrine resistance driven by sustained activation of androgen receptor (AR) signaling pathway in advanced prostate cancer (PCa) is fatal. Characterization of mechanisms underlying aberrant AR pathway activation to search for potential therapeutic strategy is particularly import...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Jiajia Wang, Hui Liu, Zeyuan Yu, Qianqian Zhou, Feifei Sun, Jingying Han, Lin Gao, Baokai Dou, Hanwen Zhang, Jiawei Fu, Wenqiao Jia, Weiwen Chen, Jing Hu, Bo Han
Hōputu: Artigo
Reo:Inglês
I whakaputaina: BMC 2024-06-01
Rangatū:Cell Communication and Signaling
Ngā marau:
Urunga tuihono:https://doi.org/10.1186/s12964-024-01703-w
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