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Synthesis and Biological Evaluation of Imidazopyridine-Isatin Hybrids as Inhibitors of Leishmania major Growth

Mahmoud A El Hassab,1 Wagdy M Eldehna,2 Zainab M Elsayed,3 Mostafa M Elbadawi,2 Ahmed T Negmeldin,4,5 Marwa Balaha,2,6 Sherry N Nasralla,7 Rehan Monir,8 Tamer M Ibrahim,2 Manabu Abe,9 Haytham O Tawfik,10 Adnan A Bekhit,7,11 Loah R Hemeda12 1Department of Medicinal Chemistry, Faculty of Pharmacy, Kin...

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Autori principali: El Hassab MA, Eldehna WM, Elsayed ZM, Elbadawi MM, Negmeldin AT, Balaha M, Nasralla SN, Monir R, Ibrahim TM, Abe M, Tawfik HO, Bekhit AA, Hemeda LR
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove Medical Press 2026-03-01
Serie:Drug Design, Development and Therapy
Soggetti:
Neglected tropical diseases
Leishmaniasis
Molecular modeling
Anti-folate mechanism
Imidazo[1
2-a]pyridine
Accesso online:https://www.dovepress.com/synthesis-and-biological-evaluation-of-imidazopyridine-isatin-hybrids--peer-reviewed-fulltext-article-DDDT
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