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The effect of neoadjuvant radiotherapy on immune cell infiltrates in myxofibrosarcoma

Background: Myxofibrosarcoma (MFS) is a subtype of soft-tissue sarcoma for which local treatment includes neoadjuvant radiotherapy (nRT) followed by surgery. The impact of nRT on the MFS tumor immune microenvironment remains unexplored. Materials and methods: Paired pre-nRT biopsy and post-nRT surge...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: M.J.L. Nederkoorn, U.E. Flucke, M.H.S. Hillebrandt-Roeffen, M.A.J. Gorris, S.G. van Ravensteijn, K. Verrijp, P.M. Braam, J.J. Bonenkamp, E.F. Dierselhuis, E. Ruijter, C. Wetzels-van der Velden, H.V.N. Kusters-Vandevelde, C.J.R. Huysentruyt, J.M.M. Grefte, J.H.W. de Wilt, I.M.E. Desar, Y.M.H. Versleijen-Jonkers
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2026-06-01
Schriftenreihe:Immuno-Oncology and Technology
Schlagworte:
myxofibrosarcoma
soft-tissue sarcoma
neoadjuvant radiotherapy
tumor immune microenvironment
immune infiltrate
Online-Zugang:http://www.sciencedirect.com/science/article/pii/S2590018826000055
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