Melatonin Activation by Human Cytochrome P450 Enzymes: A Comparison between Different Isozymes

Cytochrome P450 enzymes in the human body play a pivotal role in both the biosynthesis and the degradation of the hormone melatonin. Melatonin plays a key role in circadian rhythms in the body, but its concentration is also linked to mood fluctuations as well as emotional well-being. In the present...

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Hlavní autoři:	Thirakorn Mokkawes, Tamar De Visser, Yuanxin Cao, Sam P. De Visser
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	MDPI AG 2023-10-01
Edice:	Molecules
Témata:	cytochrome P450 enzyme catalysis enzyme mechanism computational modelling density functional theory molecular dynamics
On-line přístup:	https://www.mdpi.com/1420-3049/28/19/6961
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