Alternative malonyl-CoA pathways for microbial production of diverse products

Abstract Malonyl-CoA serves as a central precursor for the biosynthesis of diverse high-value compounds, including lipids, organic acids, and polyketides, in engineered microbial fermentation systems. However, insufficient malonyl-CoA supply often limits the production of these products. Intracellul...

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Hlavní autoři:	Kian Ghaempanah, Hengrui Zhou, Sang Yup Lee
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Springer 2026-01-01
Edice:	Applied Microbiology and Biotechnology
Témata:	Microbial cell factories Natural product Metabolic engineering Malonyl-CoA Non-carboxylative malonyl-CoA pathway Malonate assimilation
On-line přístup:	https://doi.org/10.1007/s00253-025-13679-9
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