Reduced-dose chemotherapy followed by blinatumomab for newly diagnosed philadelphia chromosome-negative B-cell precursor acute lymphoblastic leukemia: a propensity-matched comparison with hyper-CVAD

Abstract Background Philadelphia chromosome-negative B-cell acute lymphoblastic leukemia (Ph-negative BCP-ALL) accounts for a significant portion of adult cases. Blinatumomab, a bispecific T-cell engager, has shown efficacy in relapsed or refractory BCP-ALL, but its role in induction therapy with re...

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Detalhes bibliográficos

Principais autores:	Jing Lu, Yu Zhu, Huiying Qiu, Ying Wang, Xin Zhou, Haiping Dai, Xuzhang Lu, Bin Gu, Ming Hong, Miao Miao, Ruinan Lu, Jun Wang, Qian Wu, Mengxing Xue, Yun Wang, Ailing Deng, Yaoyao Shen, Yin Liu, Xueqing Dou, Yutian Lei, Xiaofei Yang, Suning Chen
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Springer 2025-02-01
coleção:	Discover Oncology
Assuntos:	B-cell precursor acute lymphoblastic leukemia Philadelphia chromosome-negative Blinatumomab Induction therapy
Acesso em linha:	https://doi.org/10.1007/s12672-025-01968-8
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