Single Stem Cell Imaging and Analysis Reveals Telomere Length Differences in Diseased Human and Mouse Skeletal Muscles

Muscle stem cells (MuSCs) contribute to muscle regeneration following injury. In many muscle disorders, the repeated cycles of damage and repair lead to stem cell dysfunction. While telomere attrition may contribute to aberrant stem cell functions, methods to accurately measure telomere length in st...

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Detalles Bibliográficos

Principais autores:	Elisia D. Tichy, David K. Sidibe, Matthew T. Tierney, Michael J. Stec, Maryam Sharifi-Sanjani, Harish Hosalkar, Scott Mubarak, F. Brad Johnson, Alessandra Sacco, Foteini Mourkioti
Formato:	Artigo
Idioma:	Inglês
Publicado:	Elsevier 2017-10-01
Series:	Stem Cell Reports
Assuntos:	muscle stem cell satellite cell telomeres MuQ-FISH FISH fluorescence in situ hybridization fluorescence-activated cell sorting Duchenne muscular dystrophy DMD
Acceso en liña:	http://www.sciencedirect.com/science/article/pii/S2213671117303600
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