Future perspectives for potential therapeutic targeting of liquid liquid phase separation in pathological immunologic condensate signalling ensembles

Abstract Liquid-Liquid Phase Separation (LLPS) plays a crucial role in the assembly and regulation of inflammatory signalling ensembles. LLPS is a phenomenon where biomacromolecules, such as proteins and RNA, separate from a homogeneous solution, and form distinct liquid droplets or condensates. The...

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Detalhes bibliográficos

Principais autores:	Subham Sarkar, Souvik Roy, Lopamudra Choudhury
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Springer 2026-07-01
coleção:	Discover Chemistry
Assuntos:	Aggregation Autoinflammatory disorders Condensate Liquid-liquid phase separation Misfolding Nanoparticle encapsulated drug
Acesso em linha:	https://doi.org/10.1007/s44371-026-00860-w
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