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Reactivity against complementary proteinase-3 is not increased in patients with PR3-ANCA-associated vasculitis.

The etiology of anti-neutrophil cytoplasmic antibodies (ANCA) associated vasculitides (AAV) is unknown, but the association between infections and autoimmunity has been studied extensively. In 2004, a novel theory was proposed that could link infection and autoimmunity. This 'theory of autoantigen c...

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Autori principali: Henko Tadema, Cees G M Kallenberg, Coen A Stegeman, Peter Heeringa
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2011-01-01
Serie:PLoS ONE
Accesso online:http://europepmc.org/articles/PMC3060099?pdf=render
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