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Albumin does not induce IL-6 release and toll-like receptor activation in vitro: Role of endotoxin contamination and biochemical modifications

Human serum albumin (HSA) is widely used in both clinical and research settings, yet its potential to stimulate immune responses remains poorly understood. In this study, we systematically investigated various therapeutic, recombinant and plasma-derived albumin preparations for their ability to indu...

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Principais autores: Margret Paar, Vera H. Fengler, Martina Schweiger, Christine Rossmann, Christoph Nusshold, Martina Mairold, Doris Payerl, Gerhard Cvirn, Karl Oettl
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2025-01-01
coleção:BBA Advances
Assuntos:
Human serum albumin
Albumin redox state
Glycated albumin
Endotoxin contamination
Cytokine release
Toll-like receptors
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2667160325000377
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