Permanent cystathionine-β-Synthase gene knockdown promotes inflammation and oxidative stress in immortalized human adipose-derived mesenchymal stem cells, enhancing their adipogenic capacity

In the present study, we aimed to investigate the impact of permanent cystathionine-β-Synthase (CBS) gene knockdown in human telomerase reverse transcriptase (hTERT) immortalized human adipose-derived mesenchymal stem cells (ASC52telo) and in their capacity to differentiate into adipocytes. CBS gene...

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Bibliografische Detailangaben

Hauptverfasser:	Ferran Comas, Jèssica Latorre, Francisco Ortega, Núria Oliveras-Cañellas, Aina Lluch, Wifredo Ricart, José Manuel Fernández-Real, José María Moreno-Navarrete
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Elsevier 2021-06-01
Schriftenreihe:	Redox Biology
Schlagworte:	Human adipose-derived mesenchymal stem cells Cystathionine β-synthase Cellular senescence Inflammation Oxidative stress and adipogenesis
Online-Zugang:	http://www.sciencedirect.com/science/article/pii/S2213231720308739
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