Noisy splicing drives mRNA isoform diversity in human cells.
While the majority of multiexonic human genes show some evidence of alternative splicing, it is unclear what fraction of observed splice forms is functionally relevant. In this study, we examine the extent of alternative splicing in human cells using deep RNA sequencing and de novo identification of...
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| Principais autores: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Public Library of Science (PLoS)
2010-12-01
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| 叢編: | PLoS Genetics |
| 在線閱讀: | http://europepmc.org/articles/PMC3000347?pdf=render |
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