OGG1 deficiency alters the intestinal microbiome and increases intestinal inflammation in a mouse model.

OGG1-deficient (Ogg1-/-) animals display increased propensity to age-induced and diet-induced metabolic diseases, including insulin resistance and fatty liver. Since the intestinal microbiome is increasingly understood to play a role in modulating host metabolic responses, we examined gut microbial...

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Hlavní autoři:	Holly Simon, Vladimir Vartanian, Melissa H Wong, Yusaku Nakabeppu, Priyanka Sharma, R Stephen Lloyd, Harini Sampath
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Public Library of Science (PLoS) 2020-01-01
Edice:	PLoS ONE
On-line přístup:	https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0227501&type=printable
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