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Interactions of sterols with antiestrogen-binding sites: structural requirements for high-affinity binding.

Animal and human tissues contain a microsomal protein that binds nonsteroidal antiestrogens with high affinity and specificity. The functions of these binding sites and the identity of their natural ligands are unknown. Following a report that certain sterols inhibit [3H]tamoxifen binding to this si...

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Bibliografiske detaljer
Principais autores: P L Hwang, A Matin
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 1989-02-01
Serier:Journal of Lipid Research
Online adgang:http://www.sciencedirect.com/science/article/pii/S002222752038384X
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