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Galectins use N-glycans of FGFs to capture growth factors at the cell surface and fine-tune their signaling

Abstract Fibroblast growth factors (FGFs) and their receptors (FGFRs) constitute complex signaling hubs that are crucial for the development and homeostasis of the human body. Most of FGFs are released by cells using the conventional secretory pathway and are N-glycosylated, yet the role of FGFs gly...

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Bibliografische Detailangaben
Hauptverfasser: Aleksandra Gedaj, Dominika Zukowska, Natalia Porebska, Marta Pozniak, Mateusz Krzyscik, Aleksandra Czyrek, Daniel Krowarsch, Malgorzata Zakrzewska, Jacek Otlewski, Lukasz Opalinski
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2023-05-01
Schriftenreihe:Cell Communication and Signaling
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Online-Zugang:https://doi.org/10.1186/s12964-023-01144-x
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