Complement Factor H Loss in RPE Cells Causes Retinal Degeneration in a Human RPE-Porcine Retinal Explant Co-Culture Model

Age-related Macular degeneration (AMD) is a degenerative disease of the macula affecting the elderly population. Treatment options are limited, partly due to the lack of understanding of AMD pathology and the lack of suitable research models that replicate the complexity of the human macula and the...

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Detalhes bibliográficos

Principais autores:	Angela Armento, Aparna Murali, Julia Marzi, Ana C Almansa-Garcia, Blanca Arango-Gonzalez, Ellen Kilger, Simon J Clark, Katja Schenke-Layland, Charmaine A Ramlogan-Steel, Jason C Steel, Marius Ueffing
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2021-11-01
coleção:	Biomolecules
Assuntos:	age-related macular degeneration (AMD) complement factor H (CFH) retinal pigment epithelium (RPE) cells retinal degeneration co-culture porcine retinal explants
Acesso em linha:	https://www.mdpi.com/2218-273X/11/11/1621
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