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Systems biology analysis of Brucella infected Peyer's patch reveals rapid invasion with modest transient perturbations of the host transcriptome.

Brucella melitensis causes the most severe and acute symptoms of all Brucella species in human beings and infects hosts primarily through the oral route. The epithelium covering domed villi of jejunal-ileal Peyer's patches is an important site of entry for several pathogens, including Brucella. Here...

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Auteurs principaux: Carlos A Rossetti, Kenneth L Drake, Prasad Siddavatam, Sara D Lawhon, Jairo E S Nunes, Tamara Gull, Sangeeta Khare, Robin E Everts, Harris A Lewin, Leslie Garry Adams
Format: Artigo
Langue:Inglês
Publié: Public Library of Science (PLoS) 2013-01-01
Collection:PLoS ONE
Accès en ligne:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24349118/pdf/?tool=EBI
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