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Quantitative proteomic analysis of pathological and physiological ovarian aging: model evaluation, molecular mechanisms, and identification of early biomarkers and therapeutic targets

Abstract Objectives Ovarian aging is considered the “pacemaker” and “biological clock” of systemic female aging, with early manifestations that are often insidious. In this study, we analyzed the shared and distinct molecular signatures between physiological and pathological ovarian aging models usi...

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Autores principales: Mengying Bai, Liujuan Zhang, Wenbo Wu, Ruoxin Weng, Haifeng Wu, Yuan Li, Shuyi Ling, Yuehui Zheng
Formato: Artigo
Lenguaje:Inglês
Publicado: BMC 2025-11-01
Colección:Journal of Ovarian Research
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Acceso en línea:https://doi.org/10.1186/s13048-025-01874-1
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