Immunity to Sda1 Protects against Infection by Sda1⁺ and Sda1⁻ Serotypes of Group A <i>Streptococcus</i>

Group A <i>Streptococcus</i> (GAS) causes a variety of diseases globally. The DNases in GAS promote GAS evasion of neutrophil killing by degrading neutrophil extracellular traps (NETs). Sda1 is a prophage-encoded DNase associated with virulent GAS strains. However, protective immunity against Sda1 h...

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Detalhes bibliográficos

Principais autores:	Shuai Bi, Jie Wang, Meiyi Xu, Ning Li, Beinan Wang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2022-01-01
coleção:	Vaccines
Assuntos:	group A <i>streptococcus</i> DNases Sda1 neutrophil extracellular traps pharyngeal colonization
Acesso em linha:	https://www.mdpi.com/2076-393X/10/1/102
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